Are chelating agents classified as hazardous chemicals?

Most common chelating agents are not classified as hazardous chemicals: Common chelating agents such as sodium tripolyphosphate, sodium hexametaphosphate, citric acid, sodium citrate, and triethanolamine possess relatively stable physicochemical properties and lack hazardous characteristics such as h3 flammability, explosiveness, toxicity, or corrosiveness. For example, EDTA (ethylenediaminetetraacetic acid) and its sodium salt are typical chelating agents widely used in detergents, dyeing auxiliaries, fiber treatment agents, cosmetic additives, food additives, and other fields. Under normal usage and handling conditions, they are relatively safe and do not qualify as hazardous chemicals.

Cyanide-based chelating agents: These exhibit high toxicity, such as sodium cyanide or ferrocyanide. While they form stable complexes with heavy metals, improper use or handling may pose severe hazards to human health and the environment.

Certain organic chelating agents: Some organic chelating agents may be toxic or irritating to humans. Exposure or inhalation at high concentrations can cause skin irritation, eye irritation, respiratory tract irritation, etc. For example, dithiothreitol can bind to heavy metals like copper and lead in the body and be excreted through urine, but excessive intake may lead to neurological damage.

Certain inorganic chelating agents: Some inorganic chelating agents may possess properties harmful to the environment or human health. For instance, certain nitrite-based chelating agents exhibit oxidizing and carcinogenic properties. At high concentrations, they may be irritating or corrosive, necessitating precautions to avoid contact with skin, eyes, or respiratory tract.